Acute liver failure is a rare but serious condition where the liver suddenly loses its ability to function, leading to rapid deterioration of liver function and potentially life-threatening complications. Causes include viral infections, drug reactions, toxins, and autoimmune diseases. Symptoms include jaundice, abdominal pain, nausea, vomiting, confusion, and coma. Prompt medical attention is crucial to prevent irreversible liver damage and improve outcomes. Treatment may involve supportive care, such as medications to manage symptoms and prevent complications, liver transplantation, or other interventions to address the underlying cause. Early diagnosis and intervention are essential for increasing the chances of survival.