Pediatric Immunodeficiencies are conditions in which a child's immune system is weakened, making them more susceptible to infections. These disorders can be inherited or acquired, affecting the body's ability to defend against bacteria, viruses, and fungi. Primary immunodeficiencies are often genetic, arising from defects in immune system components. Common symptoms include recurrent infections, slow healing, and growth issues. Diagnosing pediatric immunodeficiencies involves blood tests and immune system evaluations. Treatment may include immunoglobulin replacement therapy, antibiotics, or stem cell transplantation. Timely identification and management are crucial to enhance a child's immune response and improve their overall well-being.